Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Spleen cells were fused with Sp2/0-Ag14 myeloma cells.
Animals were immunized with cell membranes from UT-1.
The antibody reacts with HMG-CoA reductase (the rate limiting enzyme in the cholesterol biosynthetic pathway).
Tested and found negative for ectromelia virus (mousepox).
Liscum L, et al. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its mRNA in rat liver as studied with a monoclonal antibody and a cDNA probe. J. Biol. Chem. 258: 8450-8455, 1983. PubMed: 6688077
