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Yes

Facultative intracellular pathogen 

Genome sequencing strain (Broad Institute, USA)

Nucleotide (GenBank) : KU729082 ITS including 5.8S rRNA gene

Nucleotide (GenBank) : AF254790 Filobasidiella neoformans var. neoformans vacuolar (H+)-ATPase

Nucleotide (GenBank) : AF098972 phosphatidylinositol 3-kinase TOR1 (TOR1), complete coding sequence

Nucleotide (GenBank) : AF097888 macrolide-binding protein FKBP12 (FRR1) gene, complete coding sequence

Nucleotide (GenBank) : AF097889 macrolide-binding protein FKBP12 (FRR1) mRNA, complete coding sequence

Nucleotide (GenBank) : AACO02000000 Cryptococcus neoformans var. grubii H99, whole genome shotgun sequencing project.

Williamson PR, et al. Melanin biosynthesis in Cryptococcus neoformans. J. Bacteriol. 180: 1570-1572, 1998. PubMed: 9515929

Feldmesser M, et al. Cryptococcus neoformans is a facultative intracellular pathogen in murine pulmonary infection. Infect. Immun. 68: 4225-4237, 2000. PubMed: 10858240

del Poeta M, et al. Cryptococcus neoformans differential gene expression detected in vitro and in vivo with green fluorescent protein. Infect. Immun. 67: 1812-1820, 1999. PubMed: 10085022

Franzot SP, et al. Cryptococcus neoformans var. grubii: separate varietal status for Cryptococcus neoformans serotype A isolates. J. Clin. Microbiol. 37: 838-840, 1999. PubMed: 9986871

Cruz MC, et al. Rapamycin antifungal action is mediated via conserved complexes with FKBP12 and TOR kinase homologs in Cryptococcus neoformans. Mol. Cell. Biol. 19: 4101-4112, 1999. PubMed: 10330150

Heitman J, et al. The Cryptococcus neoformans genome sequencing project. Mycopathologia 148: 1-7, 1999.

Peter R Williamson, personal communication

Findley K, et al. Phylogeny and phenotypic characterization of pathogenic Cryptococcus species and closely related saprobic taxa in the Tremellales. Eukaryot Cell 8(3): 353-361, 2009. PubMed: 19151324

Wang H, et al. A fungal phylogeny based on 82 complete genomes using the composition vector method. BMC Evol. Biol. 9: 195, 2009. PubMed: 19664262

Ding C, et al. The copper regulon of the human fungal pathogen Cryptococcus neoformans H99. Mol. Microbiol. 81: 1560-1576, 2011. PubMed: 21819456

Meyer W. et al. Consensus multi-locus sequence typing scheme for Cryptococcus neoformans and Cryptococcus gattii. Med. Mycol. 47(6):561-570, 2009. PubMed: 19462334

Urai M, et al. Evasion of innate immune responses by the highly virulent Cryptococcus gattii by altering capsule glucuronoxylomannan structure. Front Cell Infect Microbiol 5: 101. doi: 10.3389/fcimb.2015.00101. PubMed: 26779451

Sorrell TC, et al. Cryptococcal transmigration across a model brain blood-barrier: evidence of the Trojan horse mechanism and differences between Cryptococcus neoformans var. grubii strain H99 and Cryptococcus gattii strain R265. Microbes Infect 18: 57-67, 2016. PubMed: 26369713

Movahed E, et al. Genome-wide transcription study of Cryptococcus neoformans H99 clinical strain versus environmental strains. PLoS One 10: e0137457, 2015. PubMed: 26360021

Chang YC, et al. Differences between Cryptococcus neoformans and Cryptococcus gattii in the molecular mechanisms governing utilization of D-amino acids as the sole nitrogen source. PLoS One 10: e0131865, 2015. PubMed: 26132227

Janbon G, et al. Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation. PLoS Genet 10: e1004261, 2014. PubMed: 24743168

Hagen F, et al. Recognition of seven species in the Cryptococcus gattii/Cryptococcus neoformans species complex. Fungal Genet. Biol. 78: 16-48, 2015. PubMed: 25721988

Peter R Williamson, personal communication