Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
A Gal- strain transformed with YAC12. YAC12 contains 365 kb of DNA from human chromosome 2, including approximately 30 Alu repeats
Bennett CB, et al. A double-strand break within a yeast artificial chromosome (YAC) containg human DNA can result in YAC loss, deletion, or cell lethality. Mol. Cell. Biol. 16: 4414-4425, 1996. PubMed: 8754842
