Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Strongly cell associated in vitro and in vivo except for feather follicle epithelium of infected chickens.
Stable for at least 30 years in viable cells frozen at -196°C.
Antigens detectable by immunodiffusion and immunofluorescence. Antigenically related to herpesvirus of turkeys (HVT), but distinct from infectious laryngotracheitis and duck enteritis virus.
Proportion of viral DNA composed of guanine and cytosine is 56-57%.Sevoian M, Chamberlain DM, and Counter, FT. Avian lymphomatosis. 1. Experimental reproduction of the neural and visceral forms. Vet Med 57: 500-501, 1962.
Solomon JJ, et al. Studies on the etiology of Marek's disease. I. Propagation of the agent in cell culture. Proc. Soc. Exp. Biol. Med. 127: 173-177, 1968. PubMed: 5644639
Stephens EA, et al. Characteristics of JMV Marek's disease tumor: a nonproductively infected transplantable cell lacking in rescuable Virus. J. Natl. Cancer Inst. 57: 865-874, 1976. PubMed: 187779
