This is a host for isolation of non-methylated DNA for transfer to other species.
This strain is used as a host to isolate DNA and plasmids for transformation into Streptomyces or any other organism that has a methylation-sensitive restriction system.
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
MacNeil DJ, et al. Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector. Gene 111: 61-68, 1992. PubMed: 1547955
Douglas J MacNeil, personal communication
