Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Bigelis R, Black KA. Biotransformation of L-tyrosine and L-phenylalanine to 2,5-dihydroxyphenyl-acetic acid followed by polymerization to melanin pigments. US Patent 4,877,728 dated Oct 31 1989
